Alien Syndrome game is a ROM you can play online within your browser. This Sega Master System ROM runs in our top-notch quality emulator at PlayRoms.net only. Play Alien Syndrome Sega Master game online in English USA version on your desktop, tablet, and mobile. If you liked playing this emulator then you will also be interested in similar classic titles Ben 10 Ultimate Alien: Cosmic Destruction and Contra 3: The Alien Wars. This free game belongs to the Alien and Shooting category of online retro games.